Activity T3.

Identification of possible causes of persistent atrial fibrillation using correlation analysis of the imaging-derived parameters with patient clinical data.

Sub-activity T3.1 Preparation of ethical permissions and patient/volunteer informed consents to perform the study.

Sub-activity T3.2 Patient selection, screening, characterization and study enrolment.

Sub-activity T3.2.1 Patient examination and selection based on inclusion criteria.

Sub-activity T3.2.2 Construction of a database of patient imaging and clinical data.

Sub-activity T3.3 Patient investigation and data analysis.

Sub-activity T3.3.1 Correlation analysis of imaging parameters and patient clinical data in order to identify disease-specific parameters.

Results

  • Ethical approval from the Ethics Committee of the Clinical Emergency County Hospital Cluj (No. 20117/October 04, 2016)
  • Study Protocol, Informed Consent and Standard Examination Questionnaire
  • Report on the retrospective study on patients with atrial fibrillation
  • Magnetic resonance imaging (MRI) scanning protocol
  • Ethical approval from the Ethics Committee of the Clinical Emergency County Hospital Cluj (No. 23403/B/12.10.2018) of the GDPR amendment to the ethical approval from October 04, 2016
  • Clinical trial registration on clinicaltrials.gov (NCT03584126).
  • Clinical trial database
  • Papers under preparation:
  1. 1. Good correlation between End-Diastolic, End-Systolic Volume of Left Ventricle and Left Atrial Volume determined by echocardiography and cardiac MRI. S. Manole, C. Budurea, S. Pop, A. Iliescu, S. D. Iancu, L. Popa, M. Coman, L. Szabó, V. Coman, Z. Bálint.
  2. 2. Echocardiographic biomarkers for the presence of fibrosis in patients with atrial fibrillation: a pilot study. C. Budurea*, S. Pop*, A. Iliescu, S. D. Iancu, S. Manole, L. Popa, M. Coman, V. Coman, Z. Bálint.
  • Conferences:
  1. Title: Assessment of the heart with atrial fibrillation using a magnetic resonance imaging (MRI) based method

Authors: S. Manole, L. Popa, C. Ciortea, C. Mihaela, C. Szabo, S. Sfrangeu, A. Marinescu, Z. Bálint

Conference: Romanian Congress of Radiology and Medical Imaging, October 6–8, 2017, Bucharest, Romania.

  1. Oral presentation S. Manole at the conference: Progress in Cardiology and Cardiovascular Surgery, May 17–19, 2018, Cluj-Napoca, Romania.
  2. Title: Validation of left atrium volume measured by echocardiography, compared to the standard method, magnetic resonance imaging, in healthy controls and patients with atrial fibrillation

Authors: C. Budurea, S. Pop, A. Iliescu, Ș. D. Iancu, V. Coman, S. Manole, M. Coman, L. Popa, C. Ciortea, Z. Bálint

Conference: National Congress of Cardiology, September 18–21, 2019, Sinaia, Romania

  1. Title: Cardiac MRI assessment of atrial fibrosis in atrial fibrillation

Author: M. Coman

Conference: Biomedical and Imaging Approaches in the Management of Atrial Fibrillation, November 7–9, 2019, Cluj-Napoca, Romania

  1. Title: Clinical database of patients with atrial fibrillation, the imATFIB study

Author: Sorin Pop

Conference: Biomedical and Imaging Approaches in the Management of Atrial Fibrillation, November 7–9, 2019, Cluj-Napoca, Romania

  1. Title: Global myocardial wall strain decreases in patients with atrial fibrillation: a pilot cohort study

Authors: S. Pop, C. Budurea, A.M. Iliescu, S.D. Iancu, V. Coman, S. Manole, M. Coman, C. Ciortea, Z. Bálint

Conference: EuroEcho 2019, December 4–7, 2019, Vienna, Austria

 

7).           E-poster and Oral presentation – Voice of E-Poster- Title: Initial validation of an automatic algorithm for whole heart segmentation from cardiac MRI images using atrial volume determination

Authors: R. Mărginean, S. Manole, L. Popa, M. Coman, S. Pop, C. Budurea, A. Andreica, L. Dioșan, Z. Bálint

Conference: European Congress of Radiology (ECR 2020), online-only congress, July 15–19, 2020.